Mutation of BAP1 gene passed down over centuries

(University of Hawaii Cancer Center) In the findings published in PLOS Genetics, through genetic and genealogical studies by Michele Carbone, M.D., Ph.D., director of the UH Cancer Center's Thoracic Oncology Program and colleagues, it was demonstrated that the family members were related and that they descended from a couple that immigrated to the US from Germany in the early 1700's.